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ABSTRACT. The Marfan syndrome is a rare autosomal dominant genetic disease of the connective tissue, leading to an increased risk of cardiovascular manifestations like aortic root dilatation, aortic valve regurgitation, mitral valve prolapse and mitral regurgitation. Cardiovascular complications, particularly aneurysm and aortic dissection, are the most important causes of morbidity and mortality in patients with this syndrome. Along with these changes in the aorta, mitral valve pathologies, mitral valve prolapses may also be found. In adults with Marfan syndrome, the mitral valve prolapse is associated with a progressive worsening of mitral valve dysfunction and may cause mitral regurgitation, heart failure or infectious endocarditis. pp. 27–32

Keywords: Marfan syndrome; mitral regurgitation; mitral valve prolapse; cardiac surgery; heart failure; cardiac complication

LARISA ANGHEL
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Grigore T. Popa University of Medicine,
Georgescu Institute of Cardiovascular Diseases, Iași
RADU ANDY SASCĂU
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Grigore T. Popa University of Medicine,
Georgescu Institute of Cardiovascular Diseases, Iași
MIRCEA BALASANIAN
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Grigore T. Popa University of Medicine,
Georgescu Institute of Cardiovascular Diseases, Iași
LIVIU MACOVEI
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Grigore T. Popa University of Medicine,
Georgescu Institute of Cardiovascular Diseases, Iași
IULIANA ARDELEANU
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Grigore T. Popa University of Medicine,
Institute of Cardiovascular Diseases, Iași
RODICA RADU
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Grigore T. Popa University of Medicine,
Georgescu Institute of Cardio¬vascular Diseases, Iași
CRISTIAN STĂTESCU
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Grigore T. Popa University of Medicine,
Georgescu Institute of Cardiovascular Diseases, Iași

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